Dr. Barry Flinn

Dr. Barry Flinn

Director, ISRR

Adjunct Faculty
Departments of Forestry and Horticulture
Virginia Polytechnic Institute and State University


Ph.D. (Botany) , 1992
The University of British Columbia






Plant Molecular Biology
Plant Functional Genomics
Plant Tissue Culture
Contact Information

Office: Room 124

Telephone: 434-766-6770

Fax: 434-791-3279

Email: barry.flinn@ialr.org

Curriculum Vitae

Dr. Barry Flinn Curriculum Vitae (PDF)

Publications

Publications

Journal Papers:

Flinn, B. 2008. Plant matrix metalloproteinases. 2008.

Kloosterman, B., De Koeyer, D., Griffiths, R., Flinn, B., Visser, R.G.G., and Bachem, C.W.B. 2007. The potato transcriptome: A new look at transcriptional changes during tuber development using the POCI array. (In review).

Veilleux, R.E., Oosumi, T., Wadl, P.A., Baxter, A.J., Holt, S.H., Ruiz-Rojas, J.J., Pattison, J., Flinn, B., Dan, Y., Nessler, C., and Shulaev, V. 2007. Insertional mutagenesis in the diploid strawberry, Fragaria vesca. (In review).

Li, X.-Q., Griffiths, R., De Koeyer, D., Rothwell, C., Gustafson, V., Regan, S., and Flinn, B. 2007. Functional genomic resources for potato. Can. J. Plant. Sci. (In press).

Chakravarty, B., Wang-Pruski, G., Flinn, B., Gustafson, V., and Regan, S. 2007. Genetic transformation in potato: approaches and strategies. Amer. J. Potato Res. 84: 301-311.

Li, X.-Q., Griffiths, R., Lagüe, M., De Koeyer, D.,Rothwell, C., Haroon, M., Stevens, B., Xu, C., Gustafson, V., Bonierbale, M.,Regan, S., and Flinn, B. 2007. EST sequencing and analysis from cold-stored and reconditioned potato tubers. ActaHort. 745: 491-493.

Regan, S., Gustafson, V., Mallubhotla, S.,Chakravarty, B., Bagchi, M., Siahbazi, M., Rothwell, C., Sardana, R., Goyer, C., Audy, P., Li, X.-Q., Wang-Pruski,G., De Koeyer, D., and Flinn, B.2006. Finding the perfect potato: using functional genomics to improve disease resistance and tuber quality traits. Can. J. Plant Path. 28: S247-S255.

Gustafson, V., Mallubhotla, S., MacDonnell,J., Sanyal-Bagchi, M., Chakravarty, B., Wang-Pruski, G., Rothwell, C., Audy,P., DeKoeyer, D., Siahbazi, M., Flinn,B. and Regan, S. 2006. Transformation and plant regeneration from leaf explants of Solanum tuberosum L. cv.‘Shepody’. Plant Cell Tiss. Org. Cult. 85: 361-366.

Flinn,B.,Rothwell, C., Griffiths, R., Lague, M., DeKoeyer, D., Sardana, R., Audy, P.,Goyer, C., Li, X-Q., Wang-Pruski, G. and Regan, S. 2005. Potato expressed sequence tag generation and analysis using standard and unique cDNAlibraries.  Plant Mol. Biol. 59(3):405-431.

Kurz, M.L., Roberts, D.R., Flinn, B.S. and Vidaver, W.E. 1994. Amorphological and biochemical analysis of embryo maturation during yellowcypress seed development. Can.J. For. Res. 24: 431-441.

Flinn,B.S.,Roberts, D.R., Newton, C.H., Cyr, D.R., Webster,F.B. and Taylor,I.E.P. 1993. Storage protein gene expression in zygotic and somatic embryos of interior spruce. Physiol. Plant. 89: 719-730.

Newton, C.H., Flinn, B.S. and Sutton, B.C.S. 1992.Vicilin-like seed storage proteins in the gymnosperm interior spruce (Piceaglauca/engelmanii). Plant Mol. Biol. 20: 315-322.

Flinn,B.S.,Roberts, D.R. and Taylor,I.E.P. 1991. Evaluation of somatic embryos of interior spruce. Characterization and developmental regulation of storage proteins. Physiol. Plant. 82: 624-632.

Flinn,B.S.,Roberts, D.R., Webb, D.T. and Sutton, B.C.S. 1991. Storage protein changes during zygotic embryogenesis in interior spruce. Tree Physiol. 8: 71-81.

Roberts, D.R., Sutton, B.C.S. and Flinn, B.S. 1990. Synchronous and highfrequency germination of interior spruce somatic embryos following partial drying at high relative humidity. Can. J. Bot. 68: 1086-1090.

Roberts, D.R., Flinn, B.S., Webb, D.T., Webster, F.B. and Sutton, B.C.S. 1990. Abscisic acid and indole-3-butyric acid regulation of maturation andaccumulation of storage proteins in somatic embryos of interior spruce. Physiol. Plant. 78: 355-360.

Webb, D.T., Webster, F., Flinn, B.S., Roberts, D.R. and Ellis, D.D. 1989. Factors influencing the induction of embryogenic and caulogenic callus from embryos of Picea glauca and Picea engelmanii. Can. J. For. Res. 19: 1303-1308.

Roberts, D.R., Flinn, B.S., Webb, D.T., Webster, F.B. and Sutton, B.C.S. 1989. Characterization of immature embryos of interior spruce by SDS-PAGE and microscopy in relation to their competence for somatic embryogenesis. PlantCell Rep. 8: 285-288.

Flinn,B.S.,Webb, D.T. and Newcomb, W. 1989. Morphometric analysis of reserve substancesand ultrastructural changes during caulogenic determination and loss of competence in eastern white pine (Pinus strobus) cotyledons in vitro. Can. J. Bot.67: 779-789.

Ellis, D., Roberts, D., Sutton, B., Lazaroff,W., Webb, D. and Flinn, B. 1989.Transformation of white spruce and other conifer species by Agrobacteriumtumefaciens. Plant Cell Rep. 8: 16-20.

Ellis, D.D., Lazaroff, W.R., Roberts, D.R., Flinn, B.S. and Webb, D.T. 1989. The effect of antibiotics on elongation, callus and bud formation from embryonic tissue of Picea glauca. Can.J. For. Res. 19: 1343-1346.

Webb, D.T., Flinn, B.S. and Georgis, W. 1988. Micropropagation of eastern whitepine (Pinus strobus L.). Can.J. For. Res. 19: 1570-1580.

Flinn,B.S.,Webb, D.T. and Newcomb, W. 1988. The role of cell clusters and  promeristemoids in determination and competence for caulogenesis by Pinus strobus cotyledons in vitro. Can. J. Bot.66: 1556-1565.

Flinn,B.,Webb, D.T. and Georgis, W. 1986. In vitro control of caulogenesis by growth regulators and media components with embryonic explants of eastern white pine(Pinus strobus L.). Can.J. Bot. 64: 1948-1956.

Book Chapters:

Merkle, S.A., Parrott, W.A. and Flinn, B.S. 1995. Morphogenic aspects of somatic embryogenesis. In Somatic embryogenesis (T.A. Thorpe, ed.). Kluwer Academic Press, Dordrecht,pp. 155-203.

Roberts, D.R., Webster, F.B., Flinn, B.S., Lazaroff, W.R. and Cyr,D.R. 1993. Somatic embryogenesis of spruce. In SynSeeds: Application of Synthetic Seeds to Crop Improvement (K. Redenbaugh, ed.). CRC Press, Boca Raton, pp. 427-450.

Roberts, D.R., Webster, F.B., Flinn, B.S., Lazaroff, W.R., McInnis,S.M. and Sutton, B.C.S. 1991. Application of somatic embryogenesis to clonal propagation of interior spruce. In Woody Plant Biotechnology (M.R. Ahuja, ed.).Plenum Press, New York,pp. 157-169.

Webb, D.T. and Flinn, B.S. 1991. Eastern white pine (Pinus strobus L.). In Biotechnology in Agriculture and Forestry, Vol. 16 (Y.P.S. Bajaj, ed.). Springer-Verlag, Berlin,pp. 358-382.


Patents

Patents and Patent Filings
(Does Not Include World Filings)

Vascular-PreferredPromoters
Inventors: Phillips, Jonathan; Puthigae, Sathish; Yao, JiaLong; Flinn, Barry; Forster,Richard S.; Eagleton, Clare.
Assignee: Arborgen LLC
Patent issued: US7442786 B2   2008-10-28

Compositions affecting programmed cell death and their use in the modification of forestry plant development.  
Inventors: Flinn, Barry; Lashem, Annette.
Assignee: Genesis Research and Development Corp. Ltd.
Patent issued: US6451604 - 2002-09-17.

Methods for producing genetically modified plants, plant materials and plant products produced thereby.  
Inventors: Flinn, Barry; Cheah, Kheng Tuan.      
Assignee: Genesis Research and Development Corp. Ltd.
Patent issued: ZA2001/1818 - 2001-12-24.

Methods for producing genetically modified plants, plant materials and plant products produced thereby.  
Inventors: Flinn, Barry; Cheah, Kheng Tuan.  
Assignee: Genesis Research and Development Corp. Ltd.
United States Patent Application: 20020016981.

Read more...
Home Dr. Barry Flinn


Research Interests:

My research interests over the past several years have concentrated on forestry and crop functional genomics, and the identification of genes controlling traits of interest. All of my current research projects have potential applications for new crop and/or plant product development, and fit in well with the overall mandate of the ISRR to develop research projects with potential economic and community development in Southside Virginia.

My initial graduate training involved the development of tissue culture protocols for the propagation and molecular breeding of conifers, and this interest in tissue culture has extended into my current program, with projects dealing with fir and pine somatic embryogenesis, the propagation of native deciduous azaleas, and the propagation of native wildflowers.

Another area in which I have been interested involves external signaling mechanisms in plant development. My current program involves the study of extracellular matrix-localized proteases and their role in the generation of signaling molecules.

Plants are continuously exposed to microbial populations during their lifetime. While most emphasis has been placed on plant-pathogen interactions, my interests reside in beneficial plant-microbe interactions, utilizing the benefical bacterium, Burkholderia phytofirmans. My current program involves the study of this interaction at the molecular level for both poplar and potato.

My interest in crop genomics continues on from my previous role as co-lead PI for the Genome Canada-funded project, the Canadian Potato Genome Project. One of the resources generated by this project was approximately 8,000 gain-of-function mutant potato lines. We are currently characterizing several of these mutant potato lines with interesting tuber phenotypes.



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Flinn Research Projects

  • Conifer Somatic Embryogenesis
    Conifer Somatic Embryogenesis

    Development of Somatic Embryogenesis-Based Propagation of Korean Fir

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  • Azalea Tissue Culture

    Azalea Tissue Culture

    Propagation of Native, Deciduous Azaleas Through Tissue Culture

    Read more...
  • Native Wildflower Propagation
    Native Wildflower Propagation

    Propagation of Native Wildflower Species Through Tissue Culture

    Read more...
  • Plant Matrix Metalloproteinases
    Plant Matrix Metalloproteinases

    Extracellular Matrix Metalloproteinases and Plant Development

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  • Beneficial Endophyte-Plant Interactions
    Beneficial Endophyte-Plant Interactions

    Development of Alternative Non-food Plant Feedstocks

    Read more...
  • Potato Mutant Characterization

    Potato Mutant Characterization

    Characterization of Potato Gain-of-Function Insertional Mutants

    Read more...
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